Salinomycin exerts anti‐colorectal cancer activity by targeting the β‐catenin/T‐cell factor complex

BACKGROUND AND PURPOSE: Salinomycin is a well‐known inhibitor of human cancer stem cells (CSCs). However, the molecular mechanism(s) by which salinomycin targets colorectal CSCs is poorly understood. Here, we have investigated underlying antitumour mechanisms of salinomycin in colorectal cancer cell...

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Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Wang, Zhongyuan, Zhou, Liang, Xiong, Yanpeng, Yu, Shubin, Li, Huan, Fan, Jiaoyang, Li, Fan, Su, Zijie, Song, Jiaxing, Sun, Qi, Liu, Shan‐Shan, Xia, Yuqing, Zhao, Liang, Li, Shiyue, Guo, Fang, Huang, Peng, Carson, Dennis A., Lu, Desheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Research Papers
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6692576/
https://ncbi.nlm.nih.gov/pubmed/31236922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14770
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