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Longdaysin inhibits Wnt/β-catenin signaling and exhibits antitumor activity against breast cancer
BACKGROUND: CK1 is involved in regulating Wnt/β-catenin signaling and represents a promising target for the treatment of breast cancer. A purine derivative longdaysin has recently been identified as a novel modulator of cellular circadian rhythms through targeting the protein kinases CK1δ, CK1α, and...
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| Publicado en: | Onco Targets Ther |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Dove Medical Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6368421/ https://ncbi.nlm.nih.gov/pubmed/30787621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S193024 |
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