HSD3B1 and Resistance to Androgen Deprivation Therapy in Prostate Cancer: A Multi-Cohort Study

BACKGROUND: HSD3B1(1245A>C) has been mechanistically linked to castration-resistant prostate cancer by encoding an altered enzyme that augments dihydrotestosterone synthesis. We hypothesized that men inheriting the HSD3B1(1245C) allele would exhibit resistance to androgen deprivation therapy (ADT...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Lancet Oncol
Main Authors: Hearn, Jason W.D., AbuAli, Ghada, Reichard, Chad A, Reddy, Chandana A, Magi-Galluzzi, Cristina, Chang, Kai-Hsiung, Carlson, Rachel, Rangel, Laureano, Reagan, Kevin, Davis, Brian J, Karnes, R. Jeffrey, Kohli, Manish, Tindall, Donald, Klein, Eric A, Sharifi, Nima
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135009/
https://ncbi.nlm.nih.gov/pubmed/27575027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1470-2045(16)30227-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados