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Targeting Interleukin-2-Inducible T-cell Kinase (ITK) in T-Cell Related Diseases

IL2-inducible T-cell kinase (ITK), a member of the Tec family tyrosine kinases, is the predominant Tec kinase in T cells and natural killer (NK) cells mediating T cell receptor (TCR) and Fc receptor (Fc R) initiated signal transduction. ITK deficiency results in impaired T and NK cell functions, lea...

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Bibliografiska uppgifter
I publikationen:Postdoc J
Huvudupphovsmän: Zhong, Yiming, Johnson, Amy J., Byrd, John C., Dubovsky, Jason A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134889/
https://ncbi.nlm.nih.gov/pubmed/27917390
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