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Glial pannexin1 contributes to tactile hypersensitivity in a mouse model of orofacial pain

Drug studies in animal models have implicated pannexin1 (Panx1) in various types of pain, including trigeminal hypersensitivity, neuropathic pain and migraine. However, the tested drugs have limited specificity and efficacy so that direct evidence for Panx1 contribution to pain has been lacking. We...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Hanstein, Regina, Hanani, Menachem, Scemes, Eliana, Spray, David C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133615/
https://ncbi.nlm.nih.gov/pubmed/27910899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38266
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