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Promises and pitfalls of a Pannexin1 transgenic mouse line
Gene targeting strategies have become a powerful technology for elucidating mammalian gene function. The recently generated knockout (KO)-first strategy produces a KO at the RNA processing level and also allows for the generation of conditional KO alleles by combining FLP/FRT and Cre/loxP systems, t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3648696/ https://ncbi.nlm.nih.gov/pubmed/23675350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00061 |
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