Promises and pitfalls of a Pannexin1 transgenic mouse line

Gene targeting strategies have become a powerful technology for elucidating mammalian gene function. The recently generated knockout (KO)-first strategy produces a KO at the RNA processing level and also allows for the generation of conditional KO alleles by combining FLP/FRT and Cre/loxP systems, t...

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Bibliografski detalji
Glavni autori: Hanstein, Regina, Negoro, Hiromitsu, Patel, Naman K., Charollais, Anne, Meda, Paolo, Spray, David C., Suadicani, Sylvia O., Scemes, Eliana
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2013
Teme:
Pharmacology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648696/
https://ncbi.nlm.nih.gov/pubmed/23675350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00061
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