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Glial pannexin1 contributes to tactile hypersensitivity in a mouse model of orofacial pain

Drug studies in animal models have implicated pannexin1 (Panx1) in various types of pain, including trigeminal hypersensitivity, neuropathic pain and migraine. However, the tested drugs have limited specificity and efficacy so that direct evidence for Panx1 contribution to pain has been lacking. We...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hanstein, Regina, Hanani, Menachem, Scemes, Eliana, Spray, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133615/
https://ncbi.nlm.nih.gov/pubmed/27910899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38266
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