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Optimal composite scores for longitudinal clinical trials under the linear mixed effects model
Clinical trials of chronic, progressive conditions use rate of change on continuous measures as the primary outcome measure, with slowing of progression on the measure as evidence of clinical efficacy. For clinical trials with a single prespecified primary endpoint, it is important to choose an endp...
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| Publicado no: | Pharm Stat |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5132034/ https://ncbi.nlm.nih.gov/pubmed/26223663 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pst.1701 |
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