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Improved Statistical Power of Alzheimer Clinical Trials by Item-Response Theory: Proof of Concept by Application to the Activities of Daily Living Scale

Discovery of effective treatment for Alzheimer disease (AD) depends upon the availability of outcome measures that exhibit good sensitivity to rates of longitudinal decline on global functional performance. The Alzheimer’s Disease Cooperative Study-Activities of Daily Living inventory (ADCS-ADL) is...

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Veröffentlicht in:Alzheimer Dis Assoc Disord
Hauptverfasser: Ard, M. Colin, Galasko, Douglas R., Edland, Steven D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362713/
https://ncbi.nlm.nih.gov/pubmed/22874658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0b013e318265bcc1
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