Potential implications of practice effects in Alzheimer's disease prevention trials

INTRODUCTION: Practice effects (PEs) present a potential confound in clinical trials with cognitive outcomes. A single-blind placebo run-in design, with repeated cognitive outcome assessments before randomization to treatment, can minimize effects of practice on trial outcome. METHODS: We investigat...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (N Y)
Main Authors: Jacobs, Diane M., Ard, M. Colin, Salmon, David P., Galasko, Douglas R., Bondi, Mark W., Edland, Steven D.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671629/
https://ncbi.nlm.nih.gov/pubmed/29124111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trci.2017.08.010
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