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Statistical Frailty Modeling for Quantitative Analysis of Exocytotic Events Recorded by Live Cell Imaging: Rapid Release of Insulin-Containing Granules Is Impaired in Human Diabetic β-cells

Hormones and neurotransmitters are released when secretory granules or synaptic vesicles fuse with the cell membrane, a process denoted exocytosis. Modern imaging techniques, in particular total internal reflection fluorescence (TIRF) microscopy, allow the investigator to monitor secretory granules...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Cortese, Giuliana, Gandasi, Nikhil R., Barg, Sebastian, Pedersen, Morten Gram
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5132000/
https://ncbi.nlm.nih.gov/pubmed/27907065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0167282
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