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Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver
DNA methylation at the 5-position of cytosine (5mC) is an epigenetic modification that regulates gene expression and cellular plasticity in development and disease. The ten-eleven translocation (TET) gene family oxidizes 5mC to 5-hydroxymethylcytosine (5hmC), providing an active mechanism for DNA de...
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| Publicado no: | Genome Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131824/ https://ncbi.nlm.nih.gov/pubmed/27737935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.211854.116 |
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