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Genome Wide Methylome Alterations in Lung Cancer

Aberrant cytosine 5-methylation underlies many deregulated elements of cancer. Among paired non-small cell lung cancers (NSCLC), we sought to profile DNA 5-methyl-cytosine features which may underlie genome-wide deregulation. In one of the more dense interrogations of the methylome, we sampled 1.2 m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mullapudi, Nandita, Ye, Bin, Suzuki, Masako, Fazzari, Melissa, Han, Weiguo, Shi, Miao K., Marquardt, Gaby, Lin, Juan, Wang, Tao, Keller, Steven, Zhu, Changcheng, Locker, Joseph D., Spivack, Simon D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684329/
https://ncbi.nlm.nih.gov/pubmed/26683690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143826
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