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Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver

DNA methylation at the 5-position of cytosine (5mC) is an epigenetic modification that regulates gene expression and cellular plasticity in development and disease. The ten-eleven translocation (TET) gene family oxidizes 5mC to 5-hydroxymethylcytosine (5hmC), providing an active mechanism for DNA de...

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Bibliografiska uppgifter
I publikationen:Genome Res
Huvudupphovsmän: Li, Xin, Liu, Yun, Salz, Tal, Hansen, Kasper D., Feinberg, Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131824/
https://ncbi.nlm.nih.gov/pubmed/27737935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.211854.116
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