Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain

BACKGROUND: Persistently active PKMζ has been implicated in maintaining spinal nociceptive sensitization that underlies pain hypersensitivity. However, evidence for PKMζ in the maintenance of pain hypersensitivity comes exclusively from short-term studies in males using pharmacological agents of que...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Nasir, Hibatulnaseer, Mahboubi, Hicham, Gyawali, Sandeep, Ding, Stephanie, Mickeviciute, Aiste, Ragavendran, J Vaigunda, Laferrière, André, Stochaj, Ursula, Coderre, Terence J
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131814/
https://ncbi.nlm.nih.gov/pubmed/27899695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916675347
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