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Boundary conditions for the maintenance of memory by PKMζ in neocortex

We report here that ZIP, a selective inhibitor of the atypical protein kinase C isoform PKMζ, abolishes very long-term conditioned taste aversion (CTA) associations in the insular cortex of the behaving rat, at least 3 mo after encoding. The effect of ZIP is not replicated by a general serine/threon...

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Main Authors: Shema, Reut, Hazvi, Shoshi, Sacktor, Todd C., Dudai, Yadin
格式: Artigo
語言:Inglês
出版: Cold Spring Harbor Laboratory Press 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661244/
https://ncbi.nlm.nih.gov/pubmed/19181618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.1183309
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