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Selective antagonism of TRPA1 produces limited efficacy in models of inflammatory- and neuropathic-induced mechanical hypersensitivity in rats

The transient receptor potential ankyrin 1 (TRPA1) channel has been implicated in pathophysiological processes that include asthma, cough, and inflammatory pain. Agonists of TRPA1 such as mustard oil and its key component allyl isothiocyanate (AITC) cause pain and neurogenic inflammation in humans a...

詳細記述

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書誌詳細
出版年:Mol Pain
主要な著者: Lehto, Sonya G, Weyer, Andy D, Youngblood, Beth D, Zhang, Maosheng, Yin, Ruoyuan, Wang, Weiya, Teffera, Yohannes, Cooke, Melanie, Stucky, Cheryl L, Schenkel, Laurie, Geuns-Meyer, Stephanie, Moyer, Bryan D, Wild, Kenneth D, Gavva, Narender R
フォーマット: Artigo
言語:Inglês
出版事項: SAGE Publications 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131813/
https://ncbi.nlm.nih.gov/pubmed/27899696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806916677761
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