Species-specific pharmacology of Trichloro(sulfanyl)ethyl benzamides as transient receptor potential ankyrin 1 (TRPA1) antagonists

Agonists of TRPA1 such as mustard oil and its key component AITC cause pain and neurogenic inflammation in humans and pain behavior in rodents. TRPA1 is activated by numerous reactive compounds making it a sensor for reactive compounds in the body. Failure of AITC, formalin and other reactive compou...

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Detalhes bibliográficos
Main Authors: Klionsky, Lana, Tamir, Rami, Gao, BaoXi, Wang, Weiya, Immke, David C, Nishimura, Nobuko, Gavva, Narender R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2222611/
https://ncbi.nlm.nih.gov/pubmed/18086308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-3-39
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