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Extracellular Sodium and Potassium Levels Modulate Cardiac Conduction in Mice Heterozygous Null for the Connexin43 Gene

Several studies have disagreed on measurements of cardiac conduction velocity (CV) in mice with a heterozygous knockout of the connexin gene Gja1 – a mutation that reduces the gap junction (GJ) protein, Connexin43 (Cx43) by 50%. We noted that perfusate ionic composition varied between studies and hy...

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Publicat a:Pflugers Arch
Autors principals: George, Sharon A, Sciuto, Katherine J., Lin, Joyce, Salama, Mohamed E, Keener, James P, Gourdie, Robert G, Poelzing, Steven
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131712/
https://ncbi.nlm.nih.gov/pubmed/25771952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-015-1698-0
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