Slow ventricular conduction in mice heterozygous for a connexin43 null mutation.

To characterize the role of the gap junction protein connexin43 (Cx43) in ventricular conduction, we studied hearts of mice with targeted deletion of the Cx43 gene. Mice homozygous for the Cx43 null mutation (Cx43 -/-) die shortly after birth. Attempts to record electrical activity in neonatal Cx43...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Guerrero, P A, Schuessler, R B, Davis, L M, Beyer, E C, Johnson, C M, Yamada, K A, Saffitz, J E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1997
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC508024/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9109444/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119367
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