Replacement of connexin43 by connexin26 in transgenic mice leads to dysfunctional reproductive organs and slowed ventricular conduction in the heart

BACKGROUND: In order to further distinguish unique from general functions of connexin43, we have generated mice in which the coding region of connexin43 was replaced by that of connexin26. RESULTS: Heterozygous mothers showed impaired mammary gland development responsible for decreased lactation and...

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Hauptverfasser: Winterhager, Elke, Pielensticker, Nicole, Freyer, Jennifer, Ghanem, Alexander, Schrickel, Jan W, Kim, Jung-Sun, Behr, Rüdiger, Grümmer, Ruth, Maass, Karen, Urschel, Stephanie, Lewalter, Thorsten, Tiemann, Klaus, Simoni, Manuela, Willecke, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852306/
https://ncbi.nlm.nih.gov/pubmed/17408477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-7-26
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