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Potassium Channels in the Cx43 Gap Junction Perinexus Modulate Ephaptic Coupling: An Experimental and Modeling Study
BACKGROUND: It was recently demonstrated that cardiac sodium channels (Na(v)1.5) localized at the perinexus, an intercalated disc nanodomain associated with gap junctions (GJ), may contribute to electrical coupling between cardiac myocytes via an ephaptic mechanism. Impairment of ephaptic coupling b...
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| Pubblicato in: | Pflugers Arch |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131566/ https://ncbi.nlm.nih.gov/pubmed/27510622 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-016-1861-2 |
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