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TLR7/8 agonist induces a post-entry SAMHD1-independent block to HIV-1 infection of monocytes
BACKGROUND: Monocytes, the primary myeloid cell-type in peripheral blood, are resistant to HIV-1 infection as a result of the lentiviral restriction factor SAMHD1. Toll-like receptors recognize microbial pathogen components, inducing the expression of antiviral host proteins and proinflammatory cyto...
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| Publicado no: | Retrovirology |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131500/ https://ncbi.nlm.nih.gov/pubmed/27905985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0316-3 |
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