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Effects of pH and polysaccharides on peptide binding to class II major histocompatibility complex molecules.

The binding of immunogenic peptides to class II major histocompatibility molecules was examined at various pH values. We studied binding of peptides containing residues 52-61 from hen egg lysozyme (HEL) to I-Ak on fixed peritoneal macrophages or to solubilized affinity-purified I-Ak. Optimum binding...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Harding, C V, Roof, R W, Allen, P M, Unanue, E R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51314/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2011583/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.7.2740
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