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Effects of pH and polysaccharides on peptide binding to class II major histocompatibility complex molecules.

The binding of immunogenic peptides to class II major histocompatibility molecules was examined at various pH values. We studied binding of peptides containing residues 52-61 from hen egg lysozyme (HEL) to I-Ak on fixed peritoneal macrophages or to solubilized affinity-purified I-Ak. Optimum binding...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Harding, C V, Roof, R W, Allen, P M, Unanue, E R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC51314/
https://ncbi.nlm.nih.gov/pubmed/2011583
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