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Effects of pH and polysaccharides on peptide binding to class II major histocompatibility complex molecules.

The binding of immunogenic peptides to class II major histocompatibility molecules was examined at various pH values. We studied binding of peptides containing residues 52-61 from hen egg lysozyme (HEL) to I-Ak on fixed peritoneal macrophages or to solubilized affinity-purified I-Ak. Optimum binding...

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Bibliografiske detaljer
Main Authors: Harding, C V, Roof, R W, Allen, P M, Unanue, E R
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC51314/
https://ncbi.nlm.nih.gov/pubmed/2011583
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