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Pancreatic Inflammation Redirects Acinar to Beta Cell Reprogramming
Using a transgenic mouse model to express MafA, Pdx1, and Neurog3 (3TF) in a pancreatic acinar cell- and doxycycline-dependent manner, we discovered that the outcome of transcription factor-mediated acinar to β-like cellular reprogramming is dependent on both the magnitude of 3TF expression and on r...
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| Veröffentlicht in: | Cell Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5131369/ https://ncbi.nlm.nih.gov/pubmed/27851966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.10.068 |
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