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Mutations in the Human AAA(+) Chaperone p97 and Related Diseases

A number of neurodegenerative diseases have been linked to mutations in the human protein p97, an abundant cytosolic AAA(+) (ATPase associated with various cellular activities) ATPase, that functions in a large number of cellular pathways. With the assistance of a variety of cofactors and adaptor pr...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Tang, Wai Kwan, Xia, Di
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5131264/
https://ncbi.nlm.nih.gov/pubmed/27990419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2016.00079
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