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Negative Allosteric Modulators Selective for The NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains

Antidepressant activity of N-methyl-D-aspartate (NMDA) receptor antagonists and negative allosteric modulators (NAMs) has led to increased investigation of their behavioral pharmacology. NMDA antagonists, such as ketamine, impair cognition in multiple species and in multiple cognitive domains. Howev...

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Опубликовано в: :Neuropsychopharmacology
Главные авторы: Weed, Michael R, Bookbinder, Mark, Polino, Joseph, Keavy, Deborah, Cardinal, Rudolf N, Simmermacher-Mayer, Jean, Cometa, Fu-ni L, King, Dalton, Thangathirupathy, Srinivasan, Macor, John E, Bristow, Linda J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130132/
https://ncbi.nlm.nih.gov/pubmed/26105137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.184
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