Negative Allosteric Modulators Selective for The NR2B Subtype of The NMDA Receptor Impair Cognition in Multiple Domains

Antidepressant activity of N-methyl-D-aspartate (NMDA) receptor antagonists and negative allosteric modulators (NAMs) has led to increased investigation of their behavioral pharmacology. NMDA antagonists, such as ketamine, impair cognition in multiple species and in multiple cognitive domains. Howev...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Weed, Michael R, Bookbinder, Mark, Polino, Joseph, Keavy, Deborah, Cardinal, Rudolf N, Simmermacher-Mayer, Jean, Cometa, Fu-ni L, King, Dalton, Thangathirupathy, Srinivasan, Macor, John E, Bristow, Linda J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130132/
https://ncbi.nlm.nih.gov/pubmed/26105137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.184
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