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Dissociating Motivational From Physiological Withdrawal in Alcohol Dependence: Role of Central Amygdala κ-Opioid Receptors

Chronic intermittent alcohol vapor exposure leads to increased dynorphin (DYN) A-like peptide expression and heightened kappa-opioid receptor (KOR) signaling in the central nucleus of the amygdala (CeA) and these neuroadaptive responses differentiate alcohol-dependent from non-dependent phenotypes....

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Publicat a:Neuropsychopharmacology
Autors principals: Kissler, Jessica L, Walker, Brendan M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130131/
https://ncbi.nlm.nih.gov/pubmed/26105136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2015.183
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