The `One-Two Punch' of Alcoholism: Role of Central Amygdala Dynorphins / Kappa-Opioid Receptors

BACKGROUND: The dynorphin (DYN)/κ-opioid receptor (KOR) system undergoes neuroadaptations following chronic alcohol exposure that promote excessive operant self-administration and negative affective-like states; however, the exact mechanisms are unknown. The present studies tested the hypothesis tha...

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Bibliografiske detaljer
Main Authors: Kissler, Jessica L., Sirohi, Sunil, Reis, Daniel J., Jansen, Heiko T., Quock, Raymond M., Smith, Daniel G., Walker, Brendan M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749293/
https://ncbi.nlm.nih.gov/pubmed/23611261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2013.03.014
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