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Suppression of progranulin expression inhibits bladder cancer growth and sensitizes cancer cells to cisplatin
We have recently demonstrated a critical role for progranulin in bladder cancer. Progranulin contributes, as an autocrine growth factor, to the transformed phenotype by modulating Akt-and MAPK-driven motility, invasion and anchorage-independent growth. Progranulin also induces F-actin remodeling by...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129986/ https://ncbi.nlm.nih.gov/pubmed/27220888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9556 |
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