Mitochondrial oxidative phosphorylation controls cancer cell's life and death decisions upon exposure to MAPK inhibitors

Although MAPK pathway inhibitors are becoming a promising anticancer strategy, they are insufficient to fully eliminate cancer cells and their long-term efficacy is strikingly limited in patients with BRAF-mutant melanomas. It is well established that BRAF inhibitors (BRAFi) hamper glucose uptake be...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Corazao-Rozas, Paola, Guerreschi, Pierre, André, Fanny, Gabert, Pierre-Elliott, Lancel, Steve, Dekiouk, Salim, Fontaine, Delphine, Tardivel, Meryem, Savina, Ariel, Quesnel, Bruno, Mortier, Laurent, Marchetti, Philippe, Kluza, Jérome
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129946/
https://ncbi.nlm.nih.gov/pubmed/27250023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7790
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