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Glucose metabolism and NRF2 coordinate the antioxidant response in melanoma resistant to MAPK inhibitors
Targeted therapies as BRAF and MEK inhibitor combination have been approved as first-line treatment for BRAF-mutant melanoma. However, disease progression occurs in most of the patients within few months of therapy. Metabolic adaptations have been described in the context of acquired resistance to B...
Shranjeno v:
| izdano v: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832419/ https://ncbi.nlm.nih.gov/pubmed/29487283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0340-4 |
| Oznake: |
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