Gastric Lgr5(+) stem cells are the cellular origin of invasive intestinal-type gastric cancer in mice

The cellular origin of gastric cancer remains elusive. Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) is the first identified marker of gastric stem cells. However, the role of Lgr5(+) stem cells in driving malignant gastric cancer is not fully validated. Here, we deleted Smad4 a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cell Res
Main Authors: Li, Xiu-Bin, Yang, Guan, Zhu, Liang, Tang, Yu-Ling, Zhang, Chong, Ju, Zhenyu, Yang, Xiao, Teng, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129876/
https://ncbi.nlm.nih.gov/pubmed/27091432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.47
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados