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Gastric Lgr5(+) stem cells are the cellular origin of invasive intestinal-type gastric cancer in mice
The cellular origin of gastric cancer remains elusive. Leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) is the first identified marker of gastric stem cells. However, the role of Lgr5(+) stem cells in driving malignant gastric cancer is not fully validated. Here, we deleted Smad4 a...
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| 出版年: | Cell Res |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129876/ https://ncbi.nlm.nih.gov/pubmed/27091432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.47 |
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