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High glucose promotes the migration of retinal pigment epithelial cells through increased oxidative stress and PEDF expression

Defects in the outer blood-retinal barrier have significant impact on the pathogenesis of diabetic retinopathy and macular edema. However, the detailed mechanisms involved remain largely unknown. This is, in part, attributed to the lack of suitable animal and cell culture models, including those of...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Am J Physiol Cell Physiol
Κύριοι συγγραφείς: Farnoodian, Mitra, Halbach, Caroline, Slinger, Cassidy, Pattnaik, Bikash R., Sorenson, Christine M., Sheibani, Nader
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Physiological Society 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129761/
https://ncbi.nlm.nih.gov/pubmed/27440660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00001.2016
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