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Expression of pigment epithelium‐derived factor and thrombospondin‐1 regulate proliferation and migration of retinal pigment epithelial cells

Age‐related macular degeneration (AMD) is the leading cause of vision loss among elderly. Although the pathogenesis of AMD is associated with retinal pigmented epithelium (RPE) dysfunction and abnormal neovascularization the detailed mechanisms remain unresolved. RPE is a specialized monolayer of ep...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Farnoodian, Mitra, Kinter, James B., Yadranji Aghdam, Saeed, Zaitoun, Ismail, Sorenson, Christine M., Sheibani, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387751/
https://ncbi.nlm.nih.gov/pubmed/25602019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12266
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