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High glucose promotes the migration of retinal pigment epithelial cells through increased oxidative stress and PEDF expression

Defects in the outer blood-retinal barrier have significant impact on the pathogenesis of diabetic retinopathy and macular edema. However, the detailed mechanisms involved remain largely unknown. This is, in part, attributed to the lack of suitable animal and cell culture models, including those of...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Farnoodian, Mitra, Halbach, Caroline, Slinger, Cassidy, Pattnaik, Bikash R., Sorenson, Christine M., Sheibani, Nader
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129761/
https://ncbi.nlm.nih.gov/pubmed/27440660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00001.2016
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