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High glucose promotes the migration of retinal pigment epithelial cells through increased oxidative stress and PEDF expression
Defects in the outer blood-retinal barrier have significant impact on the pathogenesis of diabetic retinopathy and macular edema. However, the detailed mechanisms involved remain largely unknown. This is, in part, attributed to the lack of suitable animal and cell culture models, including those of...
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| Published in: | Am J Physiol Cell Physiol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Physiological Society
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129761/ https://ncbi.nlm.nih.gov/pubmed/27440660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00001.2016 |
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