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Influence of intracellular Ca(2+) and alternative splicing on the pharmacological profile of ANO1 channels

Anoctamin-1 (ANO1) is a Ca(2+)-activated Cl(−) channel expressed in many types of cells. Splice variants of ANO1 have been shown to influence the biophysical properties of conductance. It has been suggested that several new antagonists of ANO1 with relatively high affinity and selectivity might be u...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Am J Physiol Cell Physiol
Κύριοι συγγραφείς: Sung, Tae Sik, O'Driscoll, Kate, Zheng, Haifeng, Yapp, Nicholas J., Leblanc, Normand, Koh, Sang Don, Sanders, Kenton M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Physiological Society 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129757/
https://ncbi.nlm.nih.gov/pubmed/27413167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00070.2016
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