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Influence of intracellular Ca(2+) and alternative splicing on the pharmacological profile of ANO1 channels
Anoctamin-1 (ANO1) is a Ca(2+)-activated Cl(−) channel expressed in many types of cells. Splice variants of ANO1 have been shown to influence the biophysical properties of conductance. It has been suggested that several new antagonists of ANO1 with relatively high affinity and selectivity might be u...
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| Publicado no: | Am J Physiol Cell Physiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129757/ https://ncbi.nlm.nih.gov/pubmed/27413167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00070.2016 |
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