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Efficient generation of selection‐gene‐free rat knockout models by homologous recombination in ES cells
Embryonic stem cell (ES cell)‐based rat knockout technology, although successfully developed in 2010, has seen very limited usage to date due to low targeting efficiency and a lack of optimized procedures. In this study, we performed gene targeting in ES cells from the Sprague–Dawley (SD) and the Fi...
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| 出版年: | FEBS Lett |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129459/ https://ncbi.nlm.nih.gov/pubmed/27597178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12388 |
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