Determining lower limits of detection of digital PCR assays for cancer-related gene mutations

Digital PCR offers very high sensitivity compared to many other technologies for processing molecular detection assays. Herein, a process is outlined for determining the lower limit of detection (LoD) of two droplet-based digital PCR assays for point mutations of the epidermal growth factor receptor...

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Detalhes bibliográficos
Publicado no:Biomol Detect Quantif
Main Authors: Milbury, Coren A., Zhong, Qun, Lin, Jesse, Williams, Miguel, Olson, Jeff, Link, Darren R., Hutchison, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129438/
https://ncbi.nlm.nih.gov/pubmed/27920993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bdq.2014.08.001
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