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Isoflurane Exposure Induces Cell Death, Microglial Activation and Modifies the Expression of Genes Supporting Neurodevelopment and Cognitive Function in the Male Newborn Piglet Brain

Exposure of the brain to general anesthesia during early infancy may adversely affect its neural and cognitive development. The mechanisms mediating this are complex, incompletely understood and may be sexually dimorphic, but include developmentally inappropriate apoptosis, inflammation and a disrup...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Broad, Kevin D., Hassell, Jane, Fleiss, Bobbi, Kawano, Go, Ezzati, Mojgan, Rocha-Ferreira, Eridan, Hristova, Mariya, Bennett, Kate, Fierens, Igor, Burnett, Ryan, Chaban, Badr, Alonso-Alconada, Daniel, Oliver-Taylor, Aaron, Tachsidis, Ilias, Rostami, Jamshid, Gressens, Pierre, Sanders, Robert D., Robertson, Nicola J.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127656/
https://ncbi.nlm.nih.gov/pubmed/27898690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0166784
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