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Engineering dynamical control of cell fate switching using synthetic phospho-regulons

Many cells can sense and respond to time-varying stimuli, selectively triggering changes in cell fate only in response to inputs of a particular duration or frequency. A common motif in dynamically controlled cells is a dual-timescale regulatory network: although long-term fate decisions are ultimat...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Gordley, Russell M., Williams, Reid E., Bashor, Caleb J., Toettcher, Jared E., Yan, Shude, Lim, Wendell A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127309/
https://ncbi.nlm.nih.gov/pubmed/27821768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610973113
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