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The E3 Ubiquitin Ligase TMEM129 Is a Tri-Spanning Transmembrane Protein
Misfolded proteins from the endoplasmic reticulum (ER) are transported back into the cytosol for degradation via the ubiquitin-proteasome system. The human cytomegalovirus protein US11 hijacks this ER-associated protein degradation (ERAD) pathway to downregulate human leukocyte antigen (HLA) class I...
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| Publicado no: | Viruses |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127023/ https://ncbi.nlm.nih.gov/pubmed/27854284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v8110309 |
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