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Bsd2 binds the ubiquitin ligase Rsp5 and mediates the ubiquitination of transmembrane proteins

Membrane proteins destined for the vacuolar or lysosomal lumen are typically ubiquitinated, the ubiquitin serving as a targeting signal for the multivesicular body pathway. The RING-domain ubiquitin ligase Tul1 is an integral membrane protein that modifies the yeast vacuolar enzyme carboxypeptidase...

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Détails bibliographiques
Auteurs principaux: Hettema, Ewald H, Valdez-Taubas, Javier, Pelham, Hugh R B
Format: Artigo
Langue:Inglês
Publié: 2004
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC381411/
https://ncbi.nlm.nih.gov/pubmed/14988731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600137
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