A Novel Therapeutic Peptide as a Partial Agonist of RANKL in Ischemic Stroke

The enhanced receptor activator of nuclear factor-κB (NFκB) ligand (RANKL) and its receptor (RANK) signal have been reported to attenuate ischemic brain injury through inhibition of Toll-like receptor (TLR) 4-mediated inflammation. However, augmentation of the RANKL/RANK signal also accelerates oste...

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Pubblicato in:Sci Rep
Autori principali: Kurinami, Hitomi, Shimamura, Munehisa, Nakagami, Hironori, Shimizu, Hideo, Koriyama, Hiroshi, Kawano, Tomohiro, Wakayama, Kouji, Mochizuki, Hideki, Rakugi, Hiromi, Morishita, Ryuichi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126682/
https://ncbi.nlm.nih.gov/pubmed/27897273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38062
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